Arise R. O
Name: Arise R. O
Rank: Head of Department
Department: Biochemistry

Areas of Research Interests: Enzymology, Toxicology and Drug Development

Research Focus:

Investigation of the kinetics and interactive roles of some metal ions, natural and derivatized ligands on the activities of enzymes and their efficacy and safety evaluations for malaria, diabetes and hypertension.

 


His Publications are:

  1. Rotimi O. Arise, Femi F. Bolaji., Olalekan A. Jimoh, Jospeh O. Adebayo, Femi J. Olorunniji and Sylvia O. Malomo (2005): "Regularoy Effect of Divalent Cations on Rat Liver Alkaline Phosphatase Activity: How Mg2+ activates (and inhibits) the hydrolysis of p-nitrophenylphosphate". Biokemistri 17: 129-136. (A Journal published by Nigerian Society for Experimental Biology) (Availbale online at http://www.bioline.org.br/bk)
  2. Malomo, S.O., Adebayo, J.O., Arise, R.O., Olorunniji, F.J. and Egwin, E.C. (2006): "Effects of Boungainvillea Spectabilis Leaves on Some Liver and Kidney Function indices in rats". Recent Progress in medicinal Plants. Vol. 17: 261-272. ( A Journal published by Studium Press LLC, USA)
  3. Femi J. Olorunniji, Adedoyin Igunnu, Jospeh O. Adeabyo, Rotimi, O. Arise and Sylvia O. Malomo. (2007): "Cofactor interactions in the activation of tissue non-specific alkaline phosphatase: Synergistic effects of Zn2+ and mg2+ ions". Biokemistri 19:43-48. (Available online at http://www.bioline.org.br/bk) (A Journal published by Nigerian Society for Experimental Biology).
  4. Arise, R.O., Davies, F.F., and Malomo, S.O. (2008): "Independent and interactive effects of Mg2+ and Co2+ on some kinetic parameters of rat kidney alkaline phosphatase". Scientific Research and Essay 3 (10): 488 – 494. (Available online at www.academicjournals.org/SRE).
  5. Iniaghe, O.M., Malomo, S.O., Adebayo, J.O., and Arise, R.O. (2008): "Evaluation of the antioxidant and hepatoprotective properties of the methanolic extract of Acalypha racemosa leaf in carbon tetrachloride-treated rats". African Journal of Biotechnology.7:1716 1720. (Available online at http://www.academicjournals.org/B)
  6. Arise, R.O., Davies, F.F. and Malomo, S.O. (2008): "Cobalt reverses vanadate inhibition of rat kidney alkaline phosphatase". Scientific Research and Essay 3(12): 613-620 (Available online at http://www.academicjournals.org/SRE)
  7. Arise, R.O., Malomo, S.O., Adebayo, J.O. and Igunnu, A. (2009): "Effects of aqueous extract of Eucalyptus globulus on lipid peroxidation and selected enzymes of rat liver". Journal of Medicinal Plants Research  3(2)077-081. (Available online at http://www.academicjournals.org/JMPR).
  8. Arise, R. O., Tella, A. C., Igunnu, A. and Malomo, S. O. (2010). "Elemental analysis of local galena based eyeliner and its effects on some enzymes of rat liver and brain." Int. Res. J. Biotechnol. 1(4): 059-064. Available online at  http://www.interesjournals.org/IRJOB
  9. Adebayo, J. O., Igunnu, A.,  Arise, R. O. and Malomo, S. O. (2011). "Effects of co-administration of artesunate and amodiaquine on some cardiovascular disease indices in rats." Food and  chemical Toxicology, 49(1): 45-48. Available online at http://www.sciencedirect.com/science
  10. Arise, R. O., Igunnu, A. and Malomo, S. O. (2011). "Effect of admnistration of aqueous extract of bambusa vulgaris leaves on some biochemical variables of rat liver and serum." Journal of Medicinal Plants Research 5(9):1622-1626. Available online at http://www.academicjournals.org/JMPR
  11. Arise, R.O. and Malomo, S.O. (2005). Effect of Separate and Combined Administration of Ivermectin and Albendazole on the Activites of Alkaline Phosphatase and Aminotransferases of Rat Kidney. Nig. J. Pure and Appl. Sci. 20: 1774-1780. (A Journal published by Faculty of Science, University of Ilorin, Nigeria).
  12. Arise, R.O. (2009). Applications of Blood Group systems and DNA Finger Printings,  in History and Philosophy of Science in General Studies. R.O. Lasisi  and M.A. Akanji  (eds), The General Studies Division, University of Ilorin. pp81- 87.
  13. Malomo, S.O., Olorunniji, F.J., Arise, R.O., Adebayo, J.O., Adedosu, O.T. and Odutuga, A.A. (2003). Synergistic interaction between two linear inhibitors on a single enzyme: vanadate and L-phenylalanine inhibition of rat liver alkaline phosphatase. Biokemistri 13:23-30. (A Journal published by Nigerian Society for Experimental Biology) (Available online at http://www.bioline.org,br/bk).
  14. Malomo, S.O., Arise, R.O., Olorunniji, F.J., Odutuga, A.A. and Adebayo, J.O.(2003). Effects of Co-administration of Spectinomycin and Ethanol on Some  Biochemical Parameters of Rat Kidney. Nig. J. Biochem & Mol. Biol. 19(1):51- 55. (A Journal published by Nigerian Society of Biochemistry and Molecular  Biology)
  15. Arise, R.O. and Malomo, S.O (2006). Effects of Ivermectin and /or Albendazole on Some Hepatic Microsomal Components and Lipid Peroxidation in Rat. Nig J.  Biochem. & Mol. Biol. 21(1) 47-54. (A Journal published by Nigerian Society of  Biochemistry and Molecular Biology).
  16. Obaleye, J.A., Tella, A.C., and Arise, R.O. (2009). In vivo antimalarial activity and toxicological studies of some quinoline methanol metal complexes. (Advances in Natural and Applied Sciences. 3(1):43-48. (A Journal published by American Eurasian Network for Scientific Information, Department of Biological Sciences, Al  Hussein  Bin Talal University, Mann, Jordan).
  17. Arise, R.O. and Malomo, S.O. (2009). Effects  of Ivermectin and Albendazole on  some Liver and kidney Function Indices in Rats. African Journal of Biochemistry  Research.  3(5)190 197(Available online at  http://www.academicjournals.org/AJBR  (A Journal published by School of Biochemistry, University of Kwazulu-Natal,  Durban,  South Africa. ).
  18. Arise, R.O., Malomo, S.O. and Oyewole, O.I.(2012).Histological Changes in  Selected Tissues of Ivermectin and/or Albendazole Treated Rats. International Journal of Toxicology and Applied Pharmacology.2(1):1-5. Available at http://www.urpjournals)( Journal published by Universal Research Publication,India)
  19. Arise, A.K., Arise, R.O., Akintola, A.A., Idowu, O.A. and Aworh, O.C (2012). Microbial, Nutritional and Sensory Evaluation of Traditional Sundried Okra (orunla) in Selected Markets in South-Western Nigeria. Pakistan Journal of Nutrition 11(3):231-236 (A Journal published by Science Alert/Asian Network for Scientific Information)(Available at http://www.pjbs.org/pjnonline ).
  20. Arise, R.O. and Malomo, S.O. (2012). Albendazole potentiates the neurotoxic effect of ivermectin in rat. Int. J. Biol. Chem Sci. 6(1):317-327 (A Journal published by International Formulae Group, Department of Biochemistry, University of Dschang, Cameroon).
  21. Tella, A.C., Oguntoye, S.O., Osunniran, W.A. and Arise, R.O. (2012). Co-ordination compounds of n-phthaloylglycine and n-phthaloyltyrosine and their  antimicrobial activities. Appl. Chem. 45:7620-7623. (A Journal published by  Elixir Online Journal, Dipartimento di Genetica e Biologia Molecolare Università  La Sapienza, Italy ).
  22. Arise, R.O., Akintola A. A., Olarinoye, J.B. and Balogun, E.A. (2012).  Effects of Aqueous Extract of Nauclea latifolia Stem on Lipid Profile and Some Enzymes of Rat Liver and Kidney. International Journal of Pharmacology (Online First published) (Published by Science Alert, NY, U.S.A/Asian Network for Scientific Information,) (Available online at http://scialert.net/onlinefirst.php ). 
  23. Oyewole, O.I., Malomo, S.O. and Arise, R.O. (2009). Haematological evaluation in rats following administration of some antisickling agents. International Journal of Biological and Chemical Sciences (IJBCS)  3(2): 410-414. (A Journal published by International Formulae Group, Department of Biochemistry, University of Dischang. Cameroon). Available online at http://www.infor/index.php/ijbcs
  24. Arise, R.O. Malomo, S.O. and Akiode, S.O. (2011). Influence of Zn2+ and Mg2+ on Some kinetic parameters of alkaline phosphatase in Agba river water. Nigerian Journal of Biochemistry and Molecular Biology 26(2): 88-98. (A Journal published by Nigerian Society of Biochemistry and Molecular Biology).
  25. Arise, R.O., Tella, A.C., Akintola A.A., Akiode, O.S. and Malomo, S.O (2012) Toxicity evaluation of crankase oil in rats. Excli Journal 11: 219-225. (Published by University of Mainz, Germany). Available at http://www.excli/volume22.php
  26. Arise, R.O., Malomo, S.O. and Lawal, M.M. (2012). Comparative antimalarial and toxicological effects of artemisinin with methanoloic extract of Carica papaya leaves and bark of Alstonia broonai in animal models. Advances in Natural and Applied Science: 6(2): 116-123. (A Journal published by American Eurasian Network for Scientific Information, Department of Biological Sciences, Al Hussein Bin Talal University, Mann, Jordan).
  27. Igunnu, A., Arise, R.O. Adebayo, J.O. and Malomo, S.O. (2012). Metal displacement effects on monoesterase activity of calf intestinal alkaline phosphatase. Nigerian Journal of Biochemistry and Molecular Biology 27(1):13-19. (A Journal published by Nigerian Society of Biochemistry and Molecular Biology).
  28. Arise, A.K., Arise, R.O., Muhammad, N.O., Idowu, O.A. and Akiode, S.O. (2012) Effects of storage conditions and periods on the glycoalkaloid content and nutritional value of Solanum tuberosum. Journal of Agricultural Research and Development 11(1):67-76, (Published by Faculty of Agriculture, University of Ilorin).
  29. Agboola, H.A., Arise A.K., Arise, R.O., Joseph, J.K. and Akiode, S.O. (2012). Acceptability and nutritional attributes of Moringa oleifera-enriched maize flour. Journal of Agricultural Research and Development 11(2): 353-361 (Published by Faculty of Agriculture, University of Ilorin)
  30. Arise, R.O. Akiode, S.O, Igunnu, A. and Malomo, S.O. (2012). Effect of artesunate and amodiaquine on rat hexobarbital sleeping time and some hepatic biochemical parameters. Nigerian Journal of Pure and Applied Sciences 25: 2385-2393. (A Journal published by Faculties of Life and Physical Sciences, University of Ilorin). Available online at www.njpas.com.ng
  31. Arise, R.O. and Malomo, S.O. (2013). Vitamin E attenuates toxic effects of combined administration of ivermectin and albendazole in selected rat tissues. Tropical Journal of Health Sciences 20(1): 23-30. (A Journal published by College of Health Sciences., University of Ilorin).
  32. *Arise, A.K, Arise, R.O., Esan O.T and Sanusi M.O. (2013). Quality evaluation of Moringa oleifera-fortified maize and millet. Proceeding of the 27th Annual Conference of FAMAN. Omotesho, O.A., Adewumi, M.O. Ogunlade, I., Fawole O.B, Babatunde, R.O., Ayinde, O.E and Muhammed-Lawal, A. (Eds). Pg 264-267 Published by Farm Management Association of Nigeria (FAMAN)
  33. Osioma, E., Akanji, M.A. and Arise R.O. (2013). Biotransformation and oxidative stress markers in Clariasgariepinus from petroleum exploration area in Delta State. Nigeria. NISEB Journal 13: 40-52. (A Journal published by Nigerian Society for Experimental Biology).
  34. Arise, R.O., Arise, A.K., Malomo, S.O. and Oyewole, I.O. (2013). Ivermectin protects against monosodim glutamate-induced excitotoxicity in the rat.   Advances in Food Sciences 35 (4): 153-158. The Journal is the official Journal of SECOTOX (Society of Ecotoxicology and Environmental Safety) and is published by PSP-Verlag, Freising, Germany, http://www.psp-parlar.de
  35. Osioma, F., Akanji, M.A. and Arise, R.O. (2013). Hepatic enzyme markers and proteins in serum and some selected tissues in Clariasgariepinus from swamp around Kokori-Erhoike oil field Nigeria. Journal of Research in Biology 3(4) 984-992. Available at www.jresearchbiology.com
  36. Arise, R.O., Malomo S.O. and Bolarinwa, O.A. (2013). Comparative antimalarial and safety attributes of methanolic extract of leaves of Tithoniadiversifolia and Morindalucida in animal models. American Journal of Drug Discovery and Development 3(3): 140-148. Available at http://scialert.net/onlinefirst.php?issn-2150-427x
  37. Arise, R.O., Osioma, E. and Akanji, M.A. (2013). Assessment of water quality parameters from swamps around Koriko-Erhoike Petroleum Flow Station in Delta State, Nigeria. Der Chemica Sinica 4(1): 155-161. Available online at www.pelagiaresearchlibrary.com
  38. Oyewole, O.I., Adanlawo, I.G. and Arise, R.O. (2013). Serum and tissue lipid profile in wistar rats administered leaf extract of Ficusexasperata. Annals of Biology Research 4(2): 288-291. Available at www.scholarsresearchlibrary.com
  39. Malomo, S.O., Yakubu, M.T., Amira, O.J. Dosumu, O.O., Igunnu, A., Oluwaniyi, O.O., Arise, R.O. and Adebayo, J.O. (2014). Antioxidant activities of ethyl acetate leaf extract of Celosiaargentea (Var Cristata). Nigeria Journal of Biochemistry and Molecular Biology, 29 (2): xx-xx. (A Journal published by Nigerian Society of Biochemistry and Molecular Biology)
  40. Igunnu, A., Arise, R.O., Adebayo, J.O., Olorunniji, F.J. and Malomo, S.O. (2014). Catalytic cofactors (Mg2+ and Zn2+) influence the pattern of vanadate inhibition of the monoesterase activity of calf intestinal alkaline phosphatase. Biokemistri 26(2):36-42. Journal published by Nigerian Society for Experimental Biology). Available online at http://www.bioline.org.br/bk
  41. Arise, R.O., Ganiyu, A.I. and Oguntibeju, O.O. (2014). Lipid profile antidiabetic and antioxidant activity of Acaciaataxacantha bark extract in streptozotocin-induced diabetic rats. Antioxidant-Antidiabetic Agents and Human Health, Prof. Oluwafemi Oguntibeju (Ed.). ISBN: 978-953-51-1215-0, InTech. DOL: 105772/57151. Available at http://www.intechopen.com/books/antioxidant
  42. A.K. Arise, R.O.Arise, M.O. Sanusi, O.T. Esan and S.A. Oyeyinka (2014) Effect of Moringaoleifera flower fortification on the nutritional quality and sensory properties of weaning food. Croatian Journal of Food Science and Technology 6(2):65-71. Published by Faculty of Food Technology, University of Osijek, Croatia, www.ptfos.unios.hr/cjfst
  43. Arise, R.O., Tella A.C., Akiode, S.O. Mustapha, I.K., Sunday-Nwaso, O.F., Oyegoke, R.A. and Murtala H.F. (2015). Mechanochemical synthesis of trimethoprim-copper and its antimalarial and safety evaluation in mice. Tropical Journal of Health Sciences (A Journal published by College of Health Sciences, University of Ilorin)
  44. Arise, R.O. Igunnu, A., Olajunyin, A and Olatomiwa, O.A. (2015). Activation of rat intestinal alkaline phosphate by taurine may be an alternative mechanism of endotexmic injury protection. Nigerian Journal of Basic and Applied Sciences, 23(1), 55-64. (A Journal published by Faculty of Science, Usman Danfodiyo University, Sokoto). Available online at http://www.ajol.infor/index.php/njbas/index
  45. Arise, R.O., Aboyewa, J.A. and Osioma E. (2015). Biochemical changes in Lumbricusterrestris and phytoaccumulation of heavy metals from Ugberikoko Petroleum Flow Station Swamps, Delta State, Nigeria. Nigerian Journal of Basic and Applied Sciences 23(2): 141-155 (A Journal published by Faculty of Science, Usman Danfodiyo University, Sokoto). Available online at http://www.ajol.infor/index.php/njbas/index.
  46. Tella, A.C., Owalude, O.S., Simon, N and Arise, R.O. (2015). Solid state synthesis of isostructural tetrachlorometallate salts of Amodiaquine: crystal structure of (CdCl4) (C20H24CIN3O) Medicinal Chemistry Research. 24: 3949-3957. (A Journal published by Springer Science, New York) http://link.springer.com/article/10.1007/s00044-015-1435-4
  47. Balogun, M., Arise, A.K., Arise, R.O., Kolawole, F and Oyebanji, O. (2015). Effect of addition of Moringaoleifera leaf on nutritional quality, microbial and sensory properties of spices. Croatian Journal of Food Technology, Biotechnology and Nutrition 11:91-94. http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=228164
  48. Arise, R.O., Idowu, O.A., Farohunbi, S.T., Abubakar, F.A and Aboyewa, J.A (2015).    Levels of Some Metals and Earthworm Phosphatase Activities in the Soil around Odo-Efo River, Ilorin, Kwara State. Centrepoint Journal (Science Edition) 21:88-105. A Journal published by The Library and Publications Committee, University of Ilorin, Ilorin, Nigeria).
  49. Arise, R.O., Osundahunsi, B.O., Farohunbi, S.T and Yekeen, A.A. (2016). Catalytic and kinetic properties of purified Eichhorniacrassipes leaf peroxidase. Environmental and Experimental Biology 14:83-90. (A Journal Published by the Faculty of Biology, University of Latvia). Available online at http://eeb.lu.lv/EEB/current/ .
  50. Arise, R.O., Akapa, T., Adigun, M.A., Yekeen A.A. and Oguntibeju O.O. (2016). Normoglycaemic, normolipidaemic and antioxidant effects of ethanolic extract of Acaciaataxacantha root in streptozotocin-induced diabetic rats. Notulae Scientia Biologicae 8(2): 144-150. Available online at http://www.notulaebiologicae.ro
  51. Arise, R.O. and Osundahunsi, B.O. (2016). Stability profile of Pistiastratiotes leaf peroxidase. Nigerian Journal of Basic and Applied Sciences (A Journal published by Faculty of Science, Usman Dan fodiyo University, Sokoto)
  52. Arise, R.O., Tella A.C., Iyiola, O.A., Ayeni, O.M., Farohunbi, S.T. and Yekeen, A.A (2016). Solventless synthesis, antimalarial and toxicity evaluation of lumefantrine-copper complex in Swiss mice. Notulae Scientia Biologicae 8:292-300 (A Journal Published by the University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca). Available online at http://www.notulaebiologicae.ro
  53. Arise, R.O., Yekeen, A.A., Ekun, O.E and Olatomiwa, O.J. (2016). Angiotensin-I converting enzyme-inhibitory, antiradical and hydrogen peroxide-scavenging properties of Citrullus lanatus seed protein hydrolysates. Ceylon Journal of Science 45: 39-52 (A Journal Published by the Faculty of Science, University of Peradeniya, Sri Lanka) Available online at http://doi.org/10.4038/cjs.v45i2.7387